NCIt definition : Myelin-oligodendrocyte glycoprotein (247 aa, 28 kDa) is encoded by the human MOG
gene. This protein plays a role in the myelination and maintenance of the myelin sheath.;
Alternative definition : CDISC: An antigen encoded by the MOG gene and is involved in the myelination of nerves
in the central nervous system. It can be considered as an autoantigen and is commonly
associated with the autoimmune diseases multiple sclerosis and other demyelinating
diseases.;
NCIt note : Autoantibodies targeting myelin-oligodendrocyte glycoprotein are associated with autoimmune
encephalomyelitis and multiple sclerosis.; Myelin-oligodendrocyte glycoprotein acts as a viral receptor for rubella virus. (UniProt);