" /> Vascular Endothelial Growth Factor Receptor 3 - CISMeF





Preferred Label : Vascular Endothelial Growth Factor Receptor 3;

NCIt synonyms : VEGFR-3; AV3; FMS-Related Tyrosine Kinase-4; FLT4; VEGFR3; Tyrosine-Protein Kinase Receptor FLT4; FMS-Related Tyrosine Kinase 4; EC 2.7.10.1; FMS-Like Tyrosine Kinase 4;

NCIt definition : Vascular endothelial growth factor receptor 3 (1363 aa, 153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine phosphorylation, lymph vessel formation and ligand-dependent signaling.;

NCIt note : A type I membrane protein tyrosine kinase receptor for VEGF-C, vascular endothelial growth factor receptor 3, contains seven immunoglobulin-like C2-type domains. Vascular endothelial growth factors, working through VEGF receptor-3, promote angiogenesis and metastatic spread of cancer cells. (from Nat Med 2001. 7:151 & 186);

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25/04/2024


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