" /> Cediranib Maleate - CISMeF





Preferred Label : Cediranib Maleate;

NCIt synonyms : AZD2171 Maleate; Quinazoline, 4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(1-pyrrolidinyl)propoxy)-;

NCIt related terms : AZD2171; Recentin;

NCIt definition : The maleate salt of an indole ether quinazoline derivative with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGFR-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of some types of cancer. Cediranib maleate may prevent the growth of new blood vessels that tumors need to grow and may kill cancer cells. It is a type of antiangiogenesis agent and a type of vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor.;

UNII : 68AYS9A614;

InChIKey : JRMGHBVACUJCRP-BTJKTKAUSA-N;

CAS number : 857036-77-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 857036-77-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Recentin;

Chemical formula : C25H27FN4O3.C4H4O4;

NSC code : 732208;

Codes from synonyms : CDR0000597183; CDR0000597182; CDR0000430872;

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12/05/2024


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