" /> Anti-VEGFR3 Monoclonal Antibody IMC-3C5 - CISMeF





Preferred Label : Anti-VEGFR3 Monoclonal Antibody IMC-3C5;

NCIt synonyms : Anti-VEGFR3 MoAb IMC-3C5;

NCIt definition : A fully-human monoclonal antibody directed against human vascular endothelial growth factor receptor 3 (VEGFR-3; Flt-4) with antiangiogenic activity. Anti-VEGFR-3 monoclonal antibody IMC-3C5 specifically binds to and inhibits VEGFR-3, which may result in inhibition of tumor angiogenesis and a decrease in tumor nutrient supply. VEGFR-3 plays a critical role in the embryonic vascular system development but is restricted postnatally to endothelial cells of lymphatic vessels and found to be expressed in many solid and hematologic malignancies.;

Molecule name : IMC-3C5;

NCI Metathesaurus CUI : CL428195;

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28/07/2025


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