NCIt definition : An orally bioavailable anilinophthalazine with potential antineoplastic activity.
Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial
growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis.
This agent also binds to and inhibits related receptor tyrosine kinases, including
platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.;
Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs
to the families of drugs called protein tyrosine kinase inhibitors and VEGF receptor
kinase inhibitors.;
UNII : 5DX9U76296;
InChIKey : YCOYDOIWSSHVCK-UHFFFAOYSA-N;
CAS number : 212141-54-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 212141-54-3
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G-SRS /a ;
Molecule name : ZK-232934; CGP-79787; PTK787; CGP 79787;
Chemical formula : C20H15ClN4;
NSC code : 719335;
Codes from synonyms : CDR0000046711; CDR0000390321;