" /> Vatalanib Succinate - CISMeF





Preferred Label : Vatalanib Succinate;

NCIt synonyms : 1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine Succinate;

NCIt related terms : Butanedioic Acid, Compd. with N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1);

NCIt definition : The succinate salt of vatalanib, an anilinophthalazine derivative, with antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.;

UNII : V5FUB77031;

InChIKey : LLDWLPRYLVPDTG-UHFFFAOYSA-N;

CAS number : 212142-18-2;

Molecule name : ZK 222584; PTK 787; CGP 79787D; PTK-787;

Chemical formula : C20H15ClN4.C4H6O4;

Codes from synonyms : 50326;

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08/05/2025


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