NCIt related terms : Butanedioic Acid, Compd. with N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
(1:1);
NCIt definition : The succinate salt of vatalanib, an anilinophthalazine derivative, with antineoplastic
activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial
growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis.
This agent also binds to and inhibits related receptor tyrosine kinases, including
platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.;
UNII : V5FUB77031;
InChIKey : LLDWLPRYLVPDTG-UHFFFAOYSA-N;
CAS number : 212142-18-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 212142-18-2
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G-SRS /a ;
Molecule name : ZK 222584; PTK 787; CGP 79787D; PTK-787;
Semantic type(s)