" /> Tivozanib Hydrochloride - CISMeF





Preferred Label : Tivozanib Hydrochloride;

NCIt synonyms : Tivozanib Monohydrochloride Monohydrate; Tivozanib Hydrochloride Hydrate;

NCIt definition : The hydrochloride salt of tivozanib, an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis.;

UNII : 8A9H4VK35Z;

InChIKey : RQXMKRRBJITKRN-UHFFFAOYSA-N;

CAS number : 682745-41-1;

Drug name : Fotivda;

NCI Metathesaurus CUI : CL553998;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
09/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.