" /> Tivozanib Hydrochloride - CISMeF





Preferred Label : Tivozanib Hydrochloride;

NCIt synonyms : Tivozanib Monohydrochloride Monohydrate; Tivozanib Hydrochloride Hydrate;

NCIt definition : The hydrochloride salt of tivozanib, an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis.;

UNII : 8A9H4VK35Z;

InChIKey : RQXMKRRBJITKRN-UHFFFAOYSA-N;

CAS number : 682745-41-1;

Drug name : Fotivda;

NCI Metathesaurus CUI : CL553998;

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21/08/2025


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