Platelet Endothelial Cell Adhesion Molecule

Preferred Label : Platelet Endothelial Cell Adhesion Molecule;

NCIt synonyms : EndoCAM; PECAM-1; PECA1; GPIIA'; PECAM1; CD31 Antigen; PECAM; Platelet Endothelial Cell Adhesion Molecule-1; Platelet and Endothelial Cell Adhesion Molecule 1; Platelet/Endothelial Cell Adhesion Molecule 1; CD31;

NCIt definition : Platelet endothelial cell adhesion molecule (738 aa, 83 kDa) is encoded by the human PECAM1 gene. This protein is involved in leukocyte transendothelial migration and angiogenesis.;

NCIt note : Cell adhesion molecules present on virtually all monocytes, platelets, and granulocytes. CD31 is highly expressed on endothelial cells and concentrated at the junctions between them.;

Details

Origin ID

C17402;

UMLS CUI

C5197492;

Currated CISMeF NLP mapping
- CD31 Ag [LOINC component]
- Lymphocyte antigen CD31 (substance) [SNOMED CT concept]
- Platelet Endothelial Cell Adhesion Molecule-1 [MeSH Descriptor]
- Platelet Endothelial Cell Adhesion Molecule-1 [MeSH concept]
OMIM relation
- Platelet-endothelial cell adhesion molecule 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PECAM1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- PECAM1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endothelial Cell [NCIt concept]
- Leukocyte [NCIt concept]
- Plasma Membrane [NCIt concept]
- Platelet [NCIt concept]
gene_product_has_biochemical_function
- Immunoglobulin Family Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Adhesion Molecules on Lymphocyte Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Cell to Cell Adhesion Signaling Pathway [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Lymphocyte Adhesion Pathway [NCIt concept]
- Monocyte Phagocytosis and Adhesion Pathway [NCIt concept]
- Neutrophil Surface Molecule Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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