Lysosome Membrane Protein 2

Preferred Label : Lysosome Membrane Protein 2;

NCIt synonyms : 85 kDa Lysosomal Membrane Sialoglycoprotein; SCARB2; LGP85; CD36L2 Antigen; Scavenger Receptor Class B Member 2; LIMP II; Lysosomal Integral Membrane Protein II; CD36 Antigen-Like 2; Lysosome Membrane Protein II;

NCIt definition : Lysosome membrane protein 2 (478 aa, 54 kDa) is encoded by the human SCARB2 gene. This protein plays a role in cell surface binding and endocytosis of glucosylceramidase and enterovirus 71.;

NCIt note : Lysosome membrane protein 2 is involved in the pathogenesis of hand-foot-mouth disease caused by enterovirus 71 and possibly coxsackievirus A16. (EntrezGene and OMIM);

Details

Origin ID

C204995;

OMIM relation
- Scavenger receptor class b, member 2 [OMIM gene]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- SCARB2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cellular Vesicle [NCIt concept]
- Endoplasmic Reticulum [NCIt concept]
- Endosome [NCIt concept]
- Exosome [NCIt concept]
- Lysosome [NCIt concept]
gene_product_has_biochemical_function
- Viral Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysosome Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Transport [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
- Receptor Signaling [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Virus-Cell Membrane Interaction [NCIt concept]

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