Neurogenic Locus Notch Homolog Protein 3

Preferred Label : Neurogenic Locus Notch Homolog Protein 3;

NCIt synonyms : NOTCH3; Notch Homolog 3; Notch 3;

NCIt definition : Neurogenic locus notch homolog protein 3 (2321 aa, 244 kDa) is encoded by the human NOTCH3 gene. This protein plays a role in both cell fate commitment and cell-cell signaling.;

Details

Origin ID

C106438;

UMLS CUI

C1452875;

Automatic exact mappings (from CISMeF team)
- Notch receptor 3 [OMIM gene]
- Notch receptor 4 [OMIM gene]
- Receptor, Notch3 [MeSH Descriptor]
- notch receptor 3 [ORDO Gene]
OMIM relation
- Notch receptor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NOTCH3 protein, human [MeSH Supplementary Concept]
- NOTCH3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NOTCH3 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- EGF-Like Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Dorso-Ventral Axis Formation Pathway [NCIt concept]
- Notch Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Fate Control [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]
is_target
- Tarextumab [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients