Receptor, Notch3

Preferred Label : Receptor, Notch3;

MeSH definition : A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.;

MeSH synonym : Notch-3 Protein; Notch 3 Protein; Notch3 Protein; Notch-3 Receptor; Notch 3 Receptor; Notch3 Receptor; Neurogenic Locus Notch Homolog Protein 3;

Details

Origin ID

D000071656;

UMLS CUI

C4255519;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Neurogenic Locus Notch Homolog Protein 3 [NCIt concept]
- Notch receptor 3 [OMIM gene]
- notch receptor 3 [ORDO Gene]
- notch receptor 3 [HGNC gene]
Record concept(s)
- Receptor, Notch3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- NOTCH3 protein, human [MeSH Supplementary Concept]
- Notch3 protein, mouse [MeSH Supplementary Concept]
- Notch3 protein, rat [MeSH Supplementary Concept]
- Notch3 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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