NK-Tumor Recognition Protein

Preferred Label : NK-Tumor Recognition Protein;

NCIt synonyms : NKTR Protein; NKTR; Natural Killer Triggering Receptor; Natural-Killer Cells Cyclophilin-Related Protein; NK-TR Protein;

NCIt definition : NK-tumor recognition protein (1462 aa, 166 kDa) is encoded by the human NKTR gene. This protein is involved in natural killer cell function and may possess proline isomerase activity.;

NCIt note : The cell surface NKTR Protein is involved in the recognition of tumor cells by large granular lymphocytes, which may kill tumor cells by an MHC-independent mechanism. The protein contains a unique amino acid structure and an external cyclophilin-related domain. (OMIM);

Details

Origin ID

C17693;

UMLS CUI

C0217511;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NKTR Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Mediated Cytotoxicity [NCIt concept]
- Cell-Mediated Immunity [NCIt concept]
- Immune Surveillance [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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