ATP-Sensitive Inward Rectifier Potassium Channel 11

Preferred Label : ATP-Sensitive Inward Rectifier Potassium Channel 11;

NCIt synonyms : Inwardly Rectifying Potassium Channel KIR6.2; KCNJ11; Inwardly-Rectifying Potassium Channel Subfamily J Member 11; Potassium Inwardly-Rectifying Channel Subfamily J Member 11; Potassium Voltage-Gated Channel Subfamily J Member 11; Inward Rectifier K( ) Channel Kir6.2; Potassium Channel, Inwardly Rectifying Subfamily J Member 11; Kir6.2; Potassium Inwardly Rectifying Channel Subfamily J Member 11;

NCIt definition : ATP-sensitive inward rectifier potassium channel 11 (390 aa, 44 kDa) is encoded by the human KCNJ11 gene. This protein is involved in potassium ion transport and, as part of the ATP-potassium channel complex with sulfonylurea receptor (SUR; ABCC8) in pancreatic beta cells, the regulation of glucose-induced insulin secretion.;

Details

Origin ID

C202642;

UMLS CUI

C1451984;

OMIM relation
- Potassium channel, inwardly rectifying, subfamily j, member 11 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KCNJ11 protein, human [MeSH concept]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- KCNJ11 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Pancreas [NCIt concept]
- Smooth Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Plasma Membrane [NCIt concept]
- Potassium Channel [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Myogenesis [NCIt concept]
- Potassium Channel Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
- Voltage-Gated Potassium Ion Channel Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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