Nuclear Pore Membrane Glycoprotein 210

Preferred Label : Nuclear Pore Membrane Glycoprotein 210;

NCIt synonyms : Pore Membrane Protein of 210 kDa; Nuclear Envelope Pore Membrane Protein POM 210; Nucleoporin 210; Nuclear Pore Protein gp210; Nucleoporin 210kDa; POM210; NUP210; Nucleoporin Nup210;

NCIt related terms : NUCLEAR PORE GLYCOPROTEIN-210; GP120;

NCIt definition : Nuclear pore membrane glycoprotein 210 (1887 aa, 205 kDa) is encoded by the human NUP210 gene. This protein plays a role in nuclear pore assembly, maintenance and functionality.;

Alternative definition : CDISC: An antigen encoded by the NUP210 gene and is essential for assembly and fusion, spacing and structural integrity of the nuclear pore. It can be considered as an autoantigen and is commonly associated with the autoimmune disease primary biliary cirrhosis.;

NCIt note : Nuclear pore membrane glycoprotein 210 is a target for antinuclear autoantibodies in primary biliary cirrhosis.;

Details

Origin ID

C200614;

OMIM relation
- Nucleoporin, 210-kd [OMIM gene]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NUP210 Gene [NCIt concept]
- Nucleoporin Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Nuclear Membrane [NCIt concept]
- Nuclear Pore Complex [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- HDAC Class II Signaling Pathway [NCIt concept]
- RANBP2-Mediated Sumoylation Transcription Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Nucleocytoplasmic Transport [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]
- mRNA Export [NCIt concept]

Keyword's position in hierarchy(ies) :

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