" /> Insulin Receptor-Related Receptor - CISMeF





Preferred Label : Insulin Receptor-Related Receptor;

NCIt synonyms : Insulin Receptor-Related Protein; IR-Related Receptor; INSRR; IRR; EC 2.7.10.1;

NCIt definition : Insulin receptor-related protein (1297 aa, 144 kDa) is encoded by the human INSRR gene. This protein plays a role in pH-mediated signaling;

NCIt note : Insulin receptor-related protein is cleaved to form an alpha and a beta subunit. The mature receptor is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains form the ligand-binding domain, while the beta chains exhibit kinase activity. (UniProt);

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29/07/2025


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