Integrin Alpha-10

Preferred Label : Integrin Alpha-10;

NCIt synonyms : ITGA10; Integrin Subunit Alpha 10;

NCIt definition : Integrin alpha-10 (1167 aa, 128 kDa) is encoded by the human ITGA10 gene. This protein plays a role in cell adhesion to collagen in the extracellular matrix.;

NCIt note : A heterodimer consisting of integrins alpha-10 (ITGA10) and beta-1 (ITGB1) is the functional, cell membrane-bound receptor for collagen.;

Details

Origin ID

C150269;

UMLS CUI

C1135757;

Automatic exact mappings (from CISMeF team)
- Integrin, alpha-10 [OMIM gene]
- integrin subunit alpha 10 [HGNC gene]
OMIM relation
- Integrin, alpha-10 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- integrin alpha10, human [MeSH concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGA10 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arf6 Trafficking Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients