Vascular Cell Adhesion Protein 1

Preferred Label : Vascular Cell Adhesion Protein 1;

NCIt synonyms : CD106 Antigen; V-CAM 1; INCAM-100; VCAM 1; Vascular Cell Adhesion Molecule 1; Vascular Cell Adhesion Molecule-1; CD106;

NCIt definition : Vascular cell adhesion protein 1 (739 aa, 81 kDa) is encoded by the human VCAM1 gene. This protein is involved in the adhesion of immune cells.;

NCIt note : Vascular cell adhesion protein 1 is a molecular target for several pharmaceutical compounds and a ligand for integrins, which are specific binding molecules in the extracelullar matrix.;

Details

Origin ID

C48214;

UMLS CUI

C3853651;

Currated CISMeF NLP mapping
- vascular cell adhesion Molecule-1 [MeSH concept]
- vascular cell adhesion molecule-1 [MeSH Descriptor]
OMIM relation
- Vascular cell adhesion molecule 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- VCAM1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Cellular Anthrax Toxin Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Local Acute Inflammatory Response Pathway [NCIt concept]
- Lymphocyte Adhesion Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- Paxillin-Dependent Alpha4/Beta1 Integrin Signaling Pathway [NCIt concept]
- Paxillin-Independent Alpha4/Beta1 and Alpha4/Beta7 Integrin Signaling Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- T-Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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