Low Affinity Immunoglobulin Gamma Fc Region Receptor II-A

Preferred Label : Low Affinity Immunoglobulin Gamma Fc Region Receptor II-A;

NCIt synonyms : IGFR2; FcGR; CD32 Antigen; Fc-Gamma-RIIA; Fc-Gamma RIIA; CD32; FCGR2; Low Affinity IgG Fc Fragment Receptor IIA; FcRIIA; FCGR2A1; FCG2; FCGR2A; Low Affinity Immunoglobulin Gamma Fc Region Receptor IIA; CD32A Antigen; IgG Fc Receptor II-a; Fc-Gamma RII-A; CD32A; Immunoglobulin G Fc Receptor IIA; IgG-Fc-Receptor-IIA; FcRII-a; IgG Fc Receptor IIA;

NCIt definition : Low affinity immunoglobulin gamma Fc region receptor II-a (317 aa, 35 kDa) is encoded by the human FCGR2A gene. This protein plays a role in the endocytosis of opsonized antigens.;

Details

Origin ID

C38553;

UMLS CUI

C1448238;

Currated CISMeF NLP mapping
- CD32 antigens [MeSH concept]
OMIM relation
- Fc gamma receptor iia [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- FCGR2A protein, human [MeSH concept]
- FCGR2A protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FCGR2A Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Fc-Gamma Receptor II [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoreceptor Tyrosine-Based Motif [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phagocytosis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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