Sodium-Dependent Serotonin Transporter

Preferred Label : Sodium-Dependent Serotonin Transporter;

NCIt synonyms : 5HTT; 5HT Transporter; SLC6A4; Solute Carrier Family 6 Member 4; 5-Hydroxytryptamine Transporter; Na /Cl- Dependent Serotonin Transporter;

NCIt definition : Sodium-dependent serotonin transporter (630 aa, 70 kDa) is encoded by the human SLC6A4 gene. This protein is involved in serotonin internalization.;

Details

Origin ID

C105876;

UMLS CUI

C1456457;

Automatic exact mappings (from CISMeF team)
- Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 [OMIM gene]
- serotonin plasma membrane transport proteins [MeSH Descriptor]
- solute carrier family 6 member 4 [HGNC gene]
OMIM relation
- Solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC6A4 protein, human [MeSH Supplementary Concept]
- SLC6A4 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC6A4 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Endosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Endocytotic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Escitalopram [NCIt concept]
- Escitalopram Oxalate [NCIt concept]
- Iodine I-123 ADAM [NCIt concept]

Keyword's position in hierarchy(ies) :

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