Importin-8 - CISMeF

Preferred Label : Importin-8;

NCIt synonyms : Imp8; IPO8; Ran-Binding Protein 8; RAN Binding Protein 8; Importin 8; RanBP8;

NCIt definition : Importin-8 (1037 aa, 120 kDa) is encoded by the human IPO8 gene. This protein plays a role in promoting the GTP-binding nuclear protein Ran-dependent nuclear localization of various cargoes.;

Details

Origin ID

C201807;

UMLS CUI

C2350694;

OMIM relation
- Importin 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IPO8 protein, human [MeSH Supplementary Concept]
- IPO8 protein, human [MeSH concept]
gene_encodes_gene_product
- IPO8 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cytoplasm [NCIt concept]
- Nuclear Membrane [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Protein Import into Nucleus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Nucleocytoplasmic Transport [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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