Neutrophil Gelatinase-Associated Lipocalin

Preferred Label : Neutrophil Gelatinase-Associated Lipocalin;

NCIt synonyms : p25; 25 kDa Alpha-2-Microglobulin-Related Subunit Of MMP-9; Oncogene 24p3; Lipocalin-2; NGAL; Oncogenic Lipocalin 24p3; Uterocalin; Siderocalin LCN2; Migration-Stimulating Factor Inhibitor;

NCIt definition : Neutrophil gelatinase-associated lipocalin (198 aa, 23 kDa) is encoded by the human LCN2 gene. This protein may play a role in iron transport, apoptosis, and innate immunity.;

NCIt note : Neutrophil gelatinase-associated lipocalin can form a complex with the protease matrix metalloproteinase-9. Formation of this complex may effect the protease activity and inhibitor susceptibility of the enzyme.;

Details

Origin ID

C71452;

UMLS CUI

C0215955;

OMIM relation
- Lipocalin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LCN2 protein, human [MeSH concept]
- LCN2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LCN2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Iron Chelation [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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