Translocator Protein

Preferred Label : Translocator Protein;

NCIt synonyms : Putative Peripheral Benzodiazepine Receptor-related Protein; Peripheral-Type Benzodiazepine Receptor/Recognition Site; Mitochondrial Benzodiazepine Receptor; Peripheral-Type Benzodiazepine Receptor; Isoquinoline Carboxamide-Binding Protein; Benzodiazepine Peripheral Binding Site; TSPO;

NCIt definition : Translocator protein (169 aa, 19 kDa) is encoded by the human TSPO gene. This protein is involved in cholesterol transport.;

NCIt note : The TSPO gene encodes an additional protein isoform called putative peripheral benzodiazepine receptor-related protein (102 aa, 11 kDa). This protein may function as a benzodiazepine receptor. The mRNA encoding this isoform is derived from a different reading frame and is produced at very low levels. (UniProt B1AH88);

Details

Origin ID

C122729;

UMLS CUI

C4049851;

Automatic exact mappings (from CISMeF team)
- Translocator protein, 18-kd [OMIM gene]
- protein translocation [MeSH concept]
- protein transport [MeSH Descriptor]
- translocator protein [HGNC gene]
OMIM relation
- Translocator protein, 18-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- TSPO protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- TSPO Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Outer Mitochondrial Membrane [NCIt concept]
gene_product_has_chemical_classification
- Mitochondrial Membrane Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Transport [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Fluorine F 18 DPA-714 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients