Claudin-1 - CISMeF

Preferred Label : Claudin-1;

NCIt synonyms : CLDN-1; Senescence-Associated Epithelial Membrane Protein 1; Claudin 1; CLDN1; Senescence-Associated Epithelial Membrane Protein;

NCIt definition : Claudin-1 (211 aa, 23 kDa) is encoded by the human CLDN1 gene. This protein is involved in the regulation of epithelial permeability.;

NCIt note : Claudin-1 acts as co-receptor for hepatitis C virus (HCV) in hepatocytes when complexed with CD81 antigen. (UniProt);

Details

Origin ID

C201776;

OMIM relation
- Claudin 1 [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CLDN1 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epithelium [NCIt concept]
gene_product_has_associated_anatomy
- Epithelial Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
- Tight Junction [NCIt concept]
gene_product_has_biochemical_function
- Viral Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Nectin Adhesion Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Anti-claudin-1 Monoclonal Antibody ALE.C04 [NCIt concept]

Keyword's position in hierarchy(ies) :

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