Interleukin-15 Receptor Subunit Alpha

Preferred Label : Interleukin-15 Receptor Subunit Alpha;

NCIt synonyms : IL-15 Receptor Subunit Alpha; IL-15R-Alpha; IL-15RA; CD215 Antigen;

NCIt definition : Interleukin-15 receptor subunit alpha (267 aa, 28 kDa) is encoded by the human IL15RA gene. This protein is involved in interleukin-dependent signaling.;

NCIt note : Interleukin-15 receptor subunit alpha is part of the heterotrimeric high-affinity interleukin-15 receptor with interleukin-2 receptor subunit beta, and cytokine receptor common subunit gamma.;

Details

Origin ID

C126970;

UMLS CUI

C4283909;

Automatic exact mappings (from CISMeF team)
- Interleukin 15 receptor, alpha [OMIM gene]
- Interleukin-15 receptor alpha subunit [MeSH concept]
- interleukin-15 receptor alpha subunit [MeSH Descriptor]
OMIM relation
- Interleukin 15 receptor, alpha [OMIM gene]
Semantic type(s)
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- IL15RA Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Interleukin-15 Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Polymer-conjugated IL-15 Receptor Agonist NKTR-255 [NCIt concept]

Keyword's position in hierarchy(ies) :

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