Interleukin-15 Receptor

Preferred Label : Interleukin-15 Receptor;

NCIt synonyms : High-Affinity Interleukin-15 Receptor; IL-15 Receptor; IL15 Receptor; IL-15R; Interleukin 15 Receptor; IL15R;

NCIt definition : A heterotrimeric complex comprised of interleukin-15 receptor subunit alpha, interleukin-2 receptor subunit beta, and cytokine receptor common subunit gamma. This receptor complex has high affinity for interleukin-15 and modulates interleukin signaling.;

Details

Origin ID

C128303;

UMLS CUI

C0300804;

Automatic exact mappings (from CISMeF team)
- interleukin-15 receptor activity [GO term]
- receptors, Interleukin-15 [MeSH concept]
- receptors, interleukin-15 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, Interleukin-15 [MeSH concept]
- receptors, interleukin-15 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Cytokine Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- Interleukin Signaling Process [NCIt concept]
has_gene_product_element
- Cytokine Receptor Common Subunit Gamma [NCIt concept]
- Interleukin-15 Receptor Subunit Alpha [NCIt concept]
- Interleukin-2 Receptor Subunit Beta [NCIt concept]
is_target
- Anti-CTLA-4 Monoclonal Antibody-IL-15/IL-15Ra Fusion Protein JK08 [NCIt concept]
- Anti-PD-1 Antibody-IL-15/IL-15Ra Fusion Protein IAP0971 [NCIt concept]
- Bifunctional TGF-beta Antagonist/IL-15 Protein Complex HCW9218 [NCIt concept]

Keyword's position in hierarchy(ies) :

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