Chimeric Antigen Receptor

Preferred Label : Chimeric Antigen Receptor;

NCIt synonyms : Artificial Antigen Receptor; CAR; Non-Native Antigen Receptor;

NCIt definition : A cell-surface receptor that has been engineered to combine novel features and specificities from various sources in order to enhance its antigen specificity. Engineered T-cells or B-cells will produce the specialized receptor that will be capable of binding to an epitope on its target cell.;

Details

Origin ID

C126108;

UMLS CUI

C4039583;

Automatic exact mappings (from CISMeF team)
- Automobile, device (physical object) [SNOMED CT concept]
- Carney complex, type 1 [OMIM Phenotype]
- Caronte [OMIM Phenotype]
- Chimeric antigen receptor (substance) [SNOMED CT concept]
- Coxsackievirus and adenovirus receptor [OMIM gene]
- No car (finding) [SNOMED CT concept]
- Nuclear receptor subfamily 1, group I, member 3 [OMIM gene]
- Receptors, Chimeric Antigen [MeSH Descriptor]
- Receptors, Chimeric Antigen [MeSH concept]
- SPG7 matrix AAA peptidase subunit, paraplegin [ORDO Gene]
- Spg7 matrix aaa peptidase subunit, paraplegin [OMIM gene]
- actomyosin contractile ring [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Chimeric antigen receptor (substance) [SNOMED CT concept]
- Receptors, Chimeric Antigen [MeSH Descriptor]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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