Tumor-Associated Calcium Signal Transducer 2

Preferred Label : Tumor-Associated Calcium Signal Transducer 2;

NCIt synonyms : 40kD Glycoprotein, Identified By Monoclonal Antibody GA733; M1S1 Protein; TROP-2; Cell Surface Glycoprotein TROP-2; TACSTD2; Epithelial Glycoprotein-1; Gastrointestinal Tumor-Associated Antigen 1; Pancreatic Carcinoma Marker Protein GA7331; GA733-1 Antigen; Pancreatic Carcinoma Marker Protein GA733-1; Membrane Component Chromosome 1 Surface Marker 1; Gastrointestinal Tumor-Associated Antigen GA7331; Tumor-Associated Calcium Signal Transducer-2; Cell Surface Glycoprotein TROP2; Trophoblast Cell Surface Protein 2;

NCIt definition : Tumor-associated calcium signal transducer 2 (323 aa, 36 kDa) is encoded by the human TACSTD2 gene. This protein is involved in calcium-dependent signaling.;

NCIt note : may function as a growth factor receptor; Associated with gelatinous drop-like corneal dystrophy;

Details

Origin ID

C18544;

UMLS CUI

C0245557;

OMIM relation
- Tumor-associated calcium signal transducer 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- TACSTD2 protein, human [MeSH concept]
- TACSTD2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- TACSTD2 Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Catumaxomab [NCIt concept]
- Edrecolomab [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-TROP-2/MMAE Antibody-drug Conjugate LCB84 [NCIt concept]
- Anti-TROP-2/Topoisomerase Inhibitor ADC MHB036C [NCIt concept]
- Anti-TROP2 Antibody-drug Conjugate BAT8008 [NCIt concept]
- Anti-TROP2 Antibody-drug Conjugate BIO-106 [NCIt concept]
- Anti-TROP2 Antibody-drug Conjugate BL-M02D1 [NCIt concept]
- Anti-TROP2-CAR-IL-15-transduced Cord Blood-derived Natural Killer Cells [NCIt concept]
- Antibody-drug Conjugate PF-06664178 [NCIt concept]
- Autologous TROP2-CAR-transduced PD-1-positive T Cells T60c [NCIt concept]
- Datopotamab Deruxtecan [NCIt concept]
- Sacituzumab Govitecan [NCIt concept]
- Sacituzumab Tirumotecan [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients