Bile Acid Receptor

Preferred Label : Bile Acid Receptor;

NCIt synonyms : RXR-Interacting Protein 14; Farnesoid X Nuclear Receptor; Farnesoid X-Activated Receptor; Nuclear Receptor Subfamily 1 Group H Member 4; Retinoid X Receptor-Interacting Protein 14; Farnesol Receptor HRR-1; NR1H4;

NCIt definition : Bile acid receptor (486 aa, 56 kDa) is encoded by the human NR1H4 gene. This protein is involved in both ligand-mediated gene expression and the metabolism of bile acids.;

Details

Origin ID

C114912;

UMLS CUI

C1173940;

Automatic exact mappings (from CISMeF team)
- Nuclear receptor subfamily 1, group h, member 4 [OMIM gene]
- farnesoid X-activated receptor [MeSH Supplementary Concept]
- farnesoid X-activated receptor [MeSH concept]
- nuclear receptor subfamily 1 group H member 4 [ORDO Gene]
- nuclear receptor subfamily 1 group H member 4 [HGNC gene]
OMIM relation
- Nuclear receptor subfamily 1, group h, member 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NR1H4 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NR1H4 Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lipid Metabolism and Toxicity Pathway [NCIt concept]
- RXR and RAR Heterodimerization with Other Nuclear Receptor Signaling Pathway [NCIt concept]
- Regulation of Cholesterol Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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