Contactin-1 - CISMeF

Preferred Label : Contactin-1;

NCIt synonyms : CNTN1;

NCIt related terms : Neural Cell Surface Protein F3; CONTACTIN 1; Glycoprotein GP135;

NCIt definition : Contactin-1 (1018 aa, 113 kDa) is encoded by the human CNTN1 gene. This protein plays a role in the development of the nervous system, including the formation of neuromuscular junction axon connections.;

Alternative definition : CDISC: An antigen encoded by the CNTN1 gene that functions as a cell adhesion molecule, and plays a role in the formation of axon connections in the developing nervous system. It can be considered as an autoantigen and is commonly associated with autoimmune neuropathies.;

NCIt note : Contactin-1 is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein.;

Details

Origin ID

C207242;

OMIM relation
- Contactin 1 [OMIM gene]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- CNTN1 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
- Synapse [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Neural Development [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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