" /> MORC Family CW-Type Zinc Finger Protein 3 - CISMeF





Preferred Label : MORC Family CW-Type Zinc Finger Protein 3;

NCIt synonyms : Nuclear Matrix Protein NXP2; Nuclear Matrix Protein 2; Zinc Finger CW-Type Coiled-Coil Domain Protein 3; Nuclear Matrix Protein NXP-2; NXP-2;

NCIt related terms : MJ ANTIGEN; MORC3; NXP2;

NCIt definition : MORC family CW-type zinc finger protein 3 (939 aa, 107 kDa) is encoded by the human MORC3 gene. This protein is involved in both RNA binding and nuclear matrix protein binding.;

Alternative definition : CDISC: An antigen encoded by the MORC3 gene that is involved in both RNA binding and nuclear matrix protein binding. It can be considered as an autoantigen and is commonly associated with the autoimmune diseases polymyositis and dermatomyositis.;

NCIt note : MORC family CW-type zinc finger protein 3 antibodies in patient sera may be a marker for cancer-associated dermatomyositis. (Arthritis & Rheumatism. 2013; 65: 2954-2962. doi: 10.1002/art.38093);

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31/07/2025


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