Tumor Suppressor Candidate 3

Preferred Label : Tumor Suppressor Candidate 3;

NCIt synonyms : N33; TUSC3; N33 Protein; Protein N33; Oligosaccharyltransferase 3 Homolog A; Putative Prostate Cancer Tumor Suppressor; Magnesium Uptake/Transporter TUSC3;

NCIt definition : Tumor suppressor candidate 3 (348 aa, 40 kDa) is encoded by the human TUSC3 gene. This protein is involved in both the transport of magnesium ions and the N-glycosylation of proteins.;

NCIt note : Tumor suppressor candidate 3 is an accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. (UniProt);

Details

Origin ID

C33960;

UMLS CUI

C1334860;

OMIM relation
- Tumor suppressor candidate 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TUSC3 protein, human [MeSH Supplementary Concept]
- TUSC3 protein, human [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- TUSC3 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- N-Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein Glycosylation [NCIt concept]
- Transport Process [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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