Serine/Threonine-Protein Kinase TBK1

Preferred Label : Serine/Threonine-Protein Kinase TBK1;

NCIt synonyms : NAK; NF-KB-Activating Kinase NAK; NF-KB-Activating Kinase; T2K; TANK Binding Kinase TBK1; TBK1; TANK-Binding Kinase 1; EC 2.7.11.1; NF-Kappa-B-Activating Kinase; TANK-Binding Kinase-1;

NCIt definition : Serine/threonine-protein kinase TBK1 (729 aa, 84 kDa) is encoded by the human TBK1 gene. This protein plays a role in the inflammatory response to microbial contamination.;

Details

Origin ID

C30077;

UMLS CUI

C1449326;

OMIM relation
- Tank-binding kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TBK1 protein, human [MeSH concept]
- TBK1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- TBK1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Inflammatory Response [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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