Kalirin - CISMeF

Preferred Label : Kalirin;

NCIt synonyms : Huntingtin-Associated Protein-Interacting Protein; Serine/Threonine-Protein Kinase with Dbl- and Pleckstrin Homology Domain; Serine/Threonine Kinase with Dbl and Pleckstrin Homology Domains; Protein Duo; EC 2.7.11.1; KALRN;

NCIt definition : Kalirin (2986 aa, 340 kDa) is encoded by the human KALRN gene. This protein plays a role in Rho guanine nucleotide exchange activity, serine/threonine-protein kinase activity and neuronal development and plasticity.;

Details

Origin ID

C185427;

UMLS CUI

C1609302;

Automatic exact mappings (from CISMeF team)
- kalirin RhoGEF kinase [HGNC gene]
OMIM relation
- Kalirin [OMIM gene]
See also inter- (CISMeF)
- Kalirin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- KALRN protein, human [MeSH Supplementary Concept]
- KALRN protein, human [MeSH concept]
Validated automatic mappings to BTNT
- KALRN protein, human [MeSH concept]
- KALRN protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KALRN Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arf6 Signaling Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Nervous System Development [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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