Protein Kinase

Preferred Label : Protein Kinase;

NCIt definition : A class of phosphotransferase proteins that posttranslationally modify protein substrates through the addition of phosphate groups.;

NCIt note : IUBMB designates protein kinases in EC 2.7.10.-, EC 2.7.11.-, EC 2.7.12.-, EC 2.7.13.- and EC 2.7.99.-.;

Details

Origin ID

C17018;

UMLS CUI

C0033640;

Automatic exact mappings (from CISMeF team)
- Protein kinase C (substance) [SNOMED CT concept]
- cyclic AMP-Dependent protein kinases [MeSH Descriptor]
- cyclic GMP-Dependent protein kinases [MeSH Descriptor]
- mitogen-activated protein kinase kinase 6 [HGNC gene]
- protein kinases [MeSH Descriptor]
- proto-oncogene proteins c-akt [MeSH Descriptor]
Biochemical function of gene products
- 5'-AMP-Activated Protein Kinase [NCIt concept]
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha [NCIt concept]
- Mitogen-Activated Protein Kinase Kinase [NCIt concept]
Currated CISMeF NLP mapping
- Protein kinase [LOINC component]
- protein kinase [SNOMED Notion]
- protein kinases [MeSH concept]
False automatic mappings
- Protein kinase (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Protein kinase [LOINC component]
- Protein kinase (substance) [SNOMED CT concept]
- protein kinase [SNOMED Notion]
- protein kinases [MeSH Descriptor]
- protein kinases [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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