proto-oncogene proteins c-akt

Preferred Label : proto-oncogene proteins c-akt;

MeSH definition : A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.; Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.;

MeSH synonym : rac pk protein; rac protein kinase; rac, proto-oncogene protein; rac-pk protein; related to a and c protein; akt proto oncogene protein; c akt proto oncogene protein; c-akt, proto-oncogene proteins; protein kinase b; proto oncogene protein akt; proto oncogene protein rac; proto-oncogene protein akt; proto-oncogene protein rac; protein, akt proto-oncogene; proto-oncogene protein, akt; akt, proto-oncogene protein; c-akt protein; c-akt proto-oncogene protein; protein, c-akt proto-oncogene; proto-oncogene protein, c-akt; protein-serine-threonine kinase (rac); related to a and c-protein; akt proto-oncogene protein; proto oncogene proteins c akt;

CISMeF synonym : EC 2.7.1.37;

MeSH hyponym : Proto-Oncogene proteins c-akt2; Proto-Oncogene proteins c-akt3; Proto-Oncogene proteins c-akt1; Proteins c-akt1, Proto-Oncogene; Proto Oncogene Proteins c akt1; c-akt1, Proto-Oncogene Proteins; AKT1 Protein Kinase; Rac-PK alpha Protein; Rac PK alpha Protein; alpha Protein, Rac-PK; Protein Kinase B alpha; Akt-alpha Protein; Akt alpha Protein; Proteins c-akt2, Proto-Oncogene; Proto Oncogene Proteins c akt2; c-akt2, Proto-Oncogene Proteins; Protein Kinase B beta; Rac-PK beta Protein; Rac PK beta Protein; AKT2 Protein Kinase; Akt-beta Protein; Akt beta Protein; Proteins c-akt3, Proto-Oncogene; Proto Oncogene Proteins c akt3; c-akt3, Proto-Oncogene Proteins; Akt-gamma Protein; Akt gamma Protein; AKT3 Protein Kinase; Protein Kinase B gamma;

MeSH Related Number : Proto-Oncogene proteins c-akt3; Proto-Oncogene proteins c-akt1; Proto-Oncogene proteins c-akt2; EC 2.7.11.1;

Registry Number MeSH : EC 2.7.11.1;

Related CAS MeSH : EC 2.7.11.1 (Proto-Oncogene proteins c-akt3); EC 2.7.11.1 (Proto-Oncogene proteins c-akt1); EC 2.7.11.1 (Proto-Oncogene proteins c-akt2);

Wikipedia link : https://en.wikipedia.org/wiki/Proto-oncogene proteins c-akt;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D051057;

UMLS CUI

C0164786;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2 [NCIt concept]
- AKT serine/threonine kinase 1 [ORDO Gene]
- AKT serine/threonine kinase 1 [HGNC gene]
- AKT serine/threonine kinase 3 [ORDO Gene]
- AKT serine/threonine kinase 3 [HGNC gene]
- Akt serine/threonine kinase 2 [OMIM gene]
- Akt serine/threonine kinase 3 [OMIM gene]
- Aurora Kinase C [NCIt concept]
- Cell Division Cycle 7-Related Protein Kinase [NCIt concept]
- Cyclin-Dependent Kinase 10 [NCIt concept]
- Cyclin-Dependent Kinase 2 [NCIt concept]
- Cyclin-Dependent Kinase 3 [NCIt concept]
- Deoxyribonucleic acid topoisomerase (substance) [SNOMED CT concept]
- Leucine-Rich Repeat Serine/Threonine-Protein Kinase 2 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 1 [NCIt concept]
- MAP Kinase-Interacting Serine/Threonine-Protein Kinase 2 [NCIt concept]
- Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 Beta [NCIt concept]
- Nik-Related Protein Kinase [NCIt concept]
- Protein [NCIt concept]
- Protein [FMA entity]
- Protein [LOINC component]
- Protein [MedDRA LLT]
- Protein (substance) [SNOMED CT concept]
- Protein C [MedDRA Preferred Term]
- Protein Info [NCIt concept]
- Protein Kinase [NCIt concept]
- Protein S [MedDRA Preferred Term]
- Protein kinase [LOINC component]
- Protein kinase (substance) [SNOMED CT concept]
- Protein kinase C (substance) [SNOMED CT concept]
- Protein name [EDAM data]
- RAC-Alpha Serine/Threonine Kinase [NCIt concept]
- RAC-Beta Serine/Threonine Kinase [NCIt concept]
- RAC-Gamma Serine/Threonine Kinase [NCIt concept]
- Serine/Threonine-Protein Kinase 33 [NCIt concept]
- Serine/Threonine-Protein Kinase Nek10 [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
- dietary proteins [MedlinePlus Topic]
- g protein [SNOMED Notion]
- obsolete protein [GO term]
- protein [EDAM format]
- protein [OBI concept]
- protein [Radlex concept]
- protein c [ATC Code]
- protein c, nos [SNOMED Notion]
- protein kinase [SNOMED Notion]
- protein s, nos [SNOMED Notion]
- protein, nos [SNOMED Notion]
- proteins [IUPAC Term]
CISMeF manual mappings
- AKT Inhibitor [NCIt concept]
Currated CISMeF NLP mapping
- Protein Kinase B [NCIt concept]
Indexing information
- 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one [MeSH Supplementary Concept]
- 1,7-bis(3,4-dihydroxyphenyl)hept-4-en-3-one oxime [MeSH Supplementary Concept]
- 1-(5-(3-methyl-1H-pyrazolo(3,4-c)pyridin-5-yl)pyridin-3-yloxy)-3-(3-(trifluoromethyl)phenyl)propan-2-amine [MeSH Supplementary Concept]
- 4-(4-chlorobenzyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)piperidin-4-amine [MeSH Supplementary Concept]
- 4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide [MeSH Supplementary Concept]
- 5-methyl-4-phenyl-1H-pyrazole [MeSH Supplementary Concept]
- 5-pyrrolopyridinyl-2-thiophenecarboxamide [MeSH Supplementary Concept]
- CTMP protein, rat [MeSH Supplementary Concept]
- ISC-4 compound [MeSH Supplementary Concept]
- NSC 177223 [MeSH Supplementary Concept]
- Trb1 protein, mouse [MeSH Supplementary Concept]
- capivasertib [MeSH Supplementary Concept]
- ipatasertib [MeSH Supplementary Concept]
Record concept(s)
- Proto-Oncogene proteins c-akt [MeSH concept]
- Proto-Oncogene proteins c-akt1 [MeSH concept]
- Proto-Oncogene proteins c-akt2 [MeSH concept]
- Proto-Oncogene proteins c-akt3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- AKT1 protein, human [MeSH Supplementary Concept]
- AKT2 protein, human [MeSH Supplementary Concept]
- AKT3 protein, human [MeSH Supplementary Concept]
- Akt1 protein, drosophila [MeSH Supplementary Concept]
- Akt1 protein, mouse [MeSH Supplementary Concept]
- Akt1 protein, rat [MeSH Supplementary Concept]
- Akt2 protein, mouse [MeSH Supplementary Concept]
- Akt2 protein, rat [MeSH Supplementary Concept]
- Akt3 protein, mouse [MeSH Supplementary Concept]
- Akt3 protein, rat [MeSH Supplementary Concept]
- akt-1 protein, C elegans [MeSH Supplementary Concept]
- akt-2 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Protein Kinase B [NCIt concept]

Keyword's position in hierarchy(ies) :

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