Serine/Threonine-Protein Kinase WNK2

Preferred Label : Serine/Threonine-Protein Kinase WNK2;

NCIt synonyms : Antigen NY-CO-43; Protein Kinase with No Lysine 2; EC 2.7.11.1; Protein Kinase Lysine-Deficient 2; Serologically Defined Colon Cancer Antigen 43;

NCIt definition : Serine/threonine-protein kinase WNK2 (2297 aa, 243 kDa) is encoded by the human WNK2 gene. This protein plays a role in the regulation of cell signaling and ion transport.;

NCI Metathesaurus CUI : CL541533;

Details

Origin ID

C143108;

UMLS CUI

C2000260;

Automatic exact mappings (from CISMeF team)
- Protein kinase, lysine-deficient 2 [OMIM gene]
OMIM relation
- Protein kinase, lysine-deficient 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- WNK2 protein, human [MeSH Supplementary Concept]
- WNK2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- WNK2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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