Ribosomal Protein S6 Kinase Alpha-1

Preferred Label : Ribosomal Protein S6 Kinase Alpha-1;

NCIt synonyms : p90S6K; MAPKAP Kinase 1a; Ribosomal Protein S6 Kinase 1; p90-RSK 1; S6K-Alpha-1; 90 kDa Ribosomal Protein S6 Kinase 1; p90RSK1; Ribosomal S6 Kinase 1; Ribosomal Protein S6 Kinase Alpha 1; S6K-Alpha 1; MAP Kinase-Activated Protein Kinase 1a; EC 2.7.11.1; MAPK-Activated Protein Kinase 1a; RPS6KA1; Mitogen-Activated Protein Kinase-Activated Protein Kinase 1a; RSK-1; MAPKAPK-1a;

NCIt definition : Ribosomal protein S6 kinase alpha-1 (735 aa, 83 kDa) is encoded by the human RPS6KA1 gene. This protein is involved in MAPK signaling and regulation of cell growth, proliferation, and differentiation.;

Details

Origin ID

C104766;

UMLS CUI

C1682310;

OMIM relation
- Ribosomal protein s6 kinase a1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RPS6KA1 protein, human [MeSH Supplementary Concept]
- RPS6KA1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- RPS6KA1 Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- FGF Signaling Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- NTRK1/MAPK Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- VEGFR3 Lymphatic Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
is_target
- AKT/RSK/S6K Inhibitor TAS0612 [NCIt concept]
- RSK1-4 Inhibitor PMD-026 [NCIt concept]

Keyword's position in hierarchy(ies) :

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