RAC-Gamma Serine/Threonine Kinase

Preferred Label : RAC-Gamma Serine/Threonine Kinase;

NCIt synonyms : V-Akt Murine Thymoma Viral Oncogene Homolog 3; AKT3; RAC-PK-Gamma; EC 2.7.11.1; PKB Gamma; STK-2; Protein Kinase Akt-3; Protein Kinase B Gamma; Protein Kinase-B Gamma;

NCIt definition : RAC-gamma serine/threonine-protein kinase (479 aa, 56 kDa) is encoded by the human AKT3 gene. This protein plays a role in protein phosphorylation, signal transduction, mitochondrial biogenesis and the regulation of caspase-dependent apoptosis.;

Details

Origin ID

C20939;

UMLS CUI

C1454182;

OMIM relation
- Akt serine/threonine kinase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AKT3 protein, human [MeSH concept]
- AKT3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AKT3 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- PH Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adipocytokine Signaling Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Nicotinate and Nicotinamide Metabolism Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- PI3K/AKT1 Signaling Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- Sphingolipid Metabolism Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 3 Signaling Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- Protein Kinase B [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Triciribine Phosphate [NCIt concept]

Keyword's position in hierarchy(ies) :

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