DNA Polymerase Epsilon Subunit 2

Preferred Label : DNA Polymerase Epsilon Subunit 2;

NCIt synonyms : POLE2; DNA Polymerase Epsilon Subunit B; DNA Polymerase II Subunit 2; EC 2.7.7.7;

NCIt definition : DNA polymerase epsilon subunit 2 (527 aa, 60 kDa) is encoded by the human POLE2 gene. This protein is involved in the replication and repair of chromosomal DNA.;

NCI Metathesaurus CUI : CL519815;

Details

Origin ID

C132125;

UMLS CUI

C4318395;

Automatic exact mappings (from CISMeF team)
- DNA polymerase epsilon 2, accessory subunit [HGNC gene]
- Polymerase, dna, epsilon-2 [OMIM gene]
OMIM relation
- Polymerase, dna, epsilon-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- POLE2 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- DNA Replication Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- G1/S Transition Checkpoint [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

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