G1/S Transition Checkpoint

Preferred Label : G1/S Transition Checkpoint;

NCIt synonyms : G1-S Restriction Point; G1/S Restriction Point;

NCIt definition : The point in G1 at which cells become committed to enter S phase and initiate DNA replication.;

Details

Origin ID

C19416;

UMLS CUI

C1517340;

Automatic exact mappings (from CISMeF team)
- G1 phase cell cycle checkpoints [MeSH Descriptor]
- cell cycle checkpoint [GO term]
Currated CISMeF NLP mapping
- G1/S transition checkpoint [GO term]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- G1/S transition checkpoint [GO term]
biological_process_has_associated_location
- Cell [NCIt concept]
biological_process_has_initiator_chemical_or_drug
- Mitogen [NCIt concept]
biological_process_has_initiator_process
- Intercellular Communication Process [NCIt concept]
biological_process_involves_gene_product
- Cyclin-Dependent Kinases Regulatory Subunit 1 [NCIt concept]
- DNA Polymerase Epsilon Catalytic Subunit A [NCIt concept]
- DNA Polymerase Epsilon Subunit 2 [NCIt concept]
- E3 Ubiquitin-Protein Ligase RFWD3 [NCIt concept]
- Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 [NCIt concept]
- F-Box Only Protein 31 [NCIt concept]
- Serine/Threonine-Protein Kinase LATS2 [NCIt concept]
- Serine/Threonine-Protein Kinase Pim-2 [NCIt concept]
- Serine/Threonine-Protein Phosphatase 6 Catalytic Subunit [NCIt concept]
biological_process_is_part_of_process
- Cell Proliferation [NCIt concept]
- G1 to S Transition Process [NCIt concept]
process_involves_gene
- CKS1B Gene [NCIt concept]
- CKS1B wt Allele [NCIt concept]
- EIF4EBP1 Gene [NCIt concept]
- EIF4EBP1 wt Allele [NCIt concept]
- FBXO31 Gene [NCIt concept]
- FBXO31 wt Allele [NCIt concept]
- PIM2 Gene [NCIt concept]
- PIM2 wt Allele [NCIt concept]
- POLE Gene [NCIt concept]
- POLE wt Allele [NCIt concept]
- POLE2 Gene [NCIt concept]
- POLE2 wt Allele [NCIt concept]
- PPP6C Gene [NCIt concept]
- PPP6C wt Allele [NCIt concept]
- RFWD3 Gene [NCIt concept]
- RFWD3 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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