Eukaryotic Translation Initiation Factor 4E-Binding Protein 1

Preferred Label : Eukaryotic Translation Initiation Factor 4E-Binding Protein 1;

NCIt synonyms : Phosphorylated Heat- and Acid-Stable Protein Regulated by Insulin 1; eIF4E-Binding Protein 1; 4E-BP1; PHAS-I; 4EBP1; EIF4EBP1;

NCIt definition : Eukaryotic translation initiation factor 4E-binding protein 1 (118 aa, 13 kDa) is encoded by the human EIF4EBP1 gene. This protein is involved in the modulation of translation and the sequestration of eukaryotic translation initiation factor 4E.;

Details

Origin ID

C91349;

UMLS CUI

C0254260;

OMIM relation
- Eukaryotic translation initiation factor 4e-binding protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EIF4EBP1 protein, human [MeSH concept]
- EIF4EBP1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EIF4EBP1 Gene [NCIt concept]
- Translation Process Gene [NCIt concept]
gene_product_has_biochemical_function
- Ligand Binding Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Insulin Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- Skeletal Muscle Hypertrophy Pathway [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
- mTOR Signaling Pathway BioCarta [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G1/S Transition Checkpoint [NCIt concept]
- Positive Regulation of Mitosis [NCIt concept]
- Translation Process [NCIt concept]
- Translational Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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