NCIt synonyms : RING Finger Protein 201; EC 2.3.2.27; RING-Type E3 Ubiquitin Transferase RFWD3; RING Finger and WD Repeat Domains-Containing Protein 3; RING Finger and WD Repeat Domain-Containing Protein 3; RFWD3;
NCIt definition : E3 ubiquitin-protein ligase RFWD3 (774 aa, 85 kDa) is encoded by the human RFWD3
gene. This protein is involved in the ubiquitination of proteins that regulate the
DNA damage checkpoint during the cell cycle.;
NCIt note : Substrates for E3 ubiquitin-protein ligase RFWD3 include cellular tumor antigen p53.
(UniProt);