DNA Polymerase Epsilon Catalytic Subunit A

Preferred Label : DNA Polymerase Epsilon Catalytic Subunit A;

NCIt synonyms : DNA Polymerase II Subunit A; POLE; EC 2.7.7.7;

NCIt definition : DNA polymerase epsilon catalytic subunit A (2286 aa, 262 kDa) is encoded by the human POLE gene. This protein is involved in both DNA repair and DNA replication.;

Details

Origin ID

C106236;

UMLS CUI

C3811771;

Automatic exact mappings (from CISMeF team)
- DNA polymerase epsilon, catalytic subunit [ORDO Gene]
- DNA polymerase epsilon, catalytic subunit [HGNC gene]
- Poles (ethnic group) [SNOMED CT concept]
- Polymerase, dna, epsilon [OMIM gene]
- pole [Radlex concept]
- poles [SNOMED Notion]
- rod [UCUM unit]
OMIM relation
- Polymerase, dna, epsilon [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- POLE Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
- DNA Replication Pathway [NCIt concept]
- Homologous Recombination Pathway [NCIt concept]
- Mismatch Repair Pathway [NCIt concept]
- Nucleotide Excision Repair Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Replication [NCIt concept]
- Excision Repair [NCIt concept]
- G1/S Transition Checkpoint [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]
- S Phase Process [NCIt concept]
- Telomere Maintenance [NCIt concept]

Keyword's position in hierarchy(ies) :

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