Activated CDC42 Kinase 1

Preferred Label : Activated CDC42 Kinase 1;

NCIt synonyms : tyrosine kinase, non-receptor, 2; Activated-p21cdc42Hs Kinase; ACK1; TNK2; ACK-1; EC 2.7.11.1; EC 2.7.10.2; Activated p21cdc42Hs Kinase; Tyrosine Kinase Non-Receptor Protein 2;

NCIt definition : Activated CDC42 kinase 1 (1038 aa, 115 kDa) is encoded by the human TNK2 gene. This protein is involved in tyrosine phosphorylation, endocytosis and signal transduction.;

NCIt note : Activated CDC42 kinase 1 also has serine/threonine kinase activity. (UniProt);

Details

Origin ID

C21341;

UMLS CUI

C1449330;

OMIM relation
- Tyrosine kinase, nonreceptor, 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TNK2 protein, human [MeSH concept]
- TNK2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- TNK2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Coated Pit [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
- UBA Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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