Triple Functional Domain Protein

Preferred Label : Triple Functional Domain Protein;

NCIt synonyms : PTPRF Interacting Protein; TRIO; PTPRF-Interacting Protein; EC 2.7.11.1;

NCIt definition : Triple functional domain protein (3097 aa, 347 kDa) is encoded by the human TRIO gene. This protein plays a role in both guanine nucleotide exchange and serine/threonine kinase activities.;

NCIt note : Protein_Plays_Role_In_Biological_Process: GDP/GTP Exchange, Membrane Ruffling;

Details

Origin ID

C30129;

UMLS CUI

C1448979;

OMIM relation
- Triple functional domain [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TRIO protein, human [MeSH Supplementary Concept]
- TRIO protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- TRIO Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Rac1 Cell Motility Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytoskeletal Modeling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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