Gene Therapy - CISMeF

Preferred Label : Gene Therapy;

NCIt synonyms : DNA Therapy; Intervention, Genetic; Gene Transfer Procedure; Molecular Biology, Gene Therapy;

NCIt related terms : GENETIC; Gene transfer;

NCIt definition : Application of genetic material (usually DNA) into cells in order to permanently correct an inherited disease or acquired disease.;

Alternative definition : NCI-GLOSS: Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the disease or to make the cancer cells more sensitive to other kinds of therapy.; CTEP: Treatment of human disease by gene transfer.; CDISC: Introduction of genetic material into cells in order to correct or treat an inherited or acquired disease.; CDISC-GLOSS: Therapy based on ex vivo or in vivo gene modification of cells using specific technologies, e.g., viral vectors and direct genome editing technologies. NOTE: A particular example of this is the therapy with gene-modified T cells (chimeric antigen receptor (CAR) T-cell therapies) used as immunotherapy in oncology. [After Natalie Mount, et al. Cell-based therapy technology classifications and translational challenge. Philos Trans R Soc Lond B Biol Sci. 2015 Oct 19; 370(1680): 20150017.] See also cell therapy, regenerative medicine therapy, regenerative medicine advanced therapy, biological product.;

NCIt note : Gene therapy techniques attempt to replace a faulty or missing gene associated with a particular disease, mediate localized delivery of a protein producing specified therapeutic effects, or introduce new cellular functions.;

Codes from synonyms : CDR0000045353;

Details

Origin ID

C15238;

UMLS CUI

C0017296;

Automatic exact mappings (from CISMeF team)
- GENETICS [ICD-9 code]
- Gene transfer [PASCAL theme]
- Genetics [EDAM topic]
- Genetics [DeCS]
- Genetics [LOINC Class]
- Genetics [IAB term]
- Genetics [PASCAL theme]
- Genetics [PASCAL theme]
- Genetics [PASCAL theme]
- cytisus [MeSH Descriptor]
- genetic [Radlex concept]
- genetic engineering [MeSH Descriptor]
- genetic engineering [MeSH concept]
- genetics [MeSH concept]
- genetics [MeSH Descriptor]
- genetics [MeSH Qualifier]
- genetics [CISMeF Metaterm]
- genets [MeSH concept]
- viverridae [MeSH Descriptor]
Semantic type(s)
- Therapeutic or Preventive Procedure [UMLS semantic type]
UMLS correspondences (same concept)
- Gene therapies [MedDRA High Level Term]
- Gene therapy (procedure) [SNOMED CT concept]
- gene therapy [Disease (Nov.)]
- gene therapy [MeSH concept]
concept_is_in_subset
- CDISC Glossary Terminology [NCIt concept]
- CDISC Protocol Terminology [NCIt concept]
- CDISC SDTM Intervention Type Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- CTRP Intervention Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

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