Desmosine - CISMeF

Preferred Label : Desmosine;

NCIt synonyms : Des; 4-[(4S)-4-Amino-4-Carboxybutyl]-1-[(5S)-5-Amino-5-Carboxypentyl]-3,5-Bis[(3S)-3-Amino-3-Carboxypropyl]Pyridinium; 6-{4-[(4S)-4-Amino-4-Carboxybutyl]-3,5-Bis[(3S)-3-Amino-3-Carboxypropyl]-1-Pyridiniumyl}-L-Norleucine; Pyridinium, 4-(4-Amino-4-Carboxybutyl)-1-(5-Amino-5-Carboxypentyl)-3,5-Bis(3-Amino-3-Carboxypropyl)-;

NCIt definition : An amino acid derivative comprised of three allysyl side chains plus one unaltered lysyl side chain from the same or neighboring polypeptides condensed into a pyridinium ring. Desmosine is found in elastin and its detection in urine, plasma, or sputum samples can be used as a marker for excessive elastin degradation, which is associated with chronic obstructive pulmonary disease (COPD) and other pathologies.;

UNII : 4MOL2J0TLY;

InChIKey : VEVRNHHLCPGNDU-MUGJNUQGSA-O;

CAS number : 11003-57-9;

ChEBI ID : CHEBI:37628;

Details

Origin ID

C124071;

UMLS CUI

C0011702;

Automatic exact mappings (from CISMeF team)
- Desmin [OMIM gene]
Currated CISMeF NLP mapping
- desmosine [MeSH concept]
- desmosine [MeSH Descriptor]
False automatic mappings
- Cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 1 [OMIM Phenotype]
- Dysequilibrium syndrome (disorder) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- desmosine [MeSH Descriptor]
- desmosine [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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