Essential Thrombocythemia

Preferred Label : Essential Thrombocythemia;

NCIt synonyms : Essential Thrombocytemia; Primary Thrombocytosis; Primary Thrombocythemia;

NCIt related terms : ET; essential thrombocytosis; Idiopathic thrombocythemia; Essential (hemorrhagic) thrombocythemia;

NCIt definition : A chronic myeloproliferative neoplasm that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage. (WHO, 2008);

Alternative definition : NCI-GLOSS: An increased number of thrombocytes (platelets) in the blood, without a known cause.; NICHD: A chronic condition that involves primarily the megakaryocytic lineage. It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and elevated risk for thrombosis and/or hemorrhage.;

Neoplastic status : Malignant;

ICD-O code : 9962/3;

Codes from synonyms : CDR0000256561; CDR0000256562; 10015493; D47.3;

Details

Origin ID

C3407;

UMLS CUI

C0040028;

Automatic exact mappings (from CISMeF team)
- Contact with health services for embryo transfer [ICD-11 Sub-sub category]
- Disorders of Eustachian tube [ICD-11 Category]
- Idiopathic thrombocythemia [ICD-9 code]
- Phosphate cytidylyltransferase 2, ethanolamine [OMIM gene]
- embryo transfer [MeSH Descriptor]
- endotoxemia [MeSH Descriptor]
- ethanolamine-phosphate cytidylyltransferase activity [GO term]
Currated CISMeF NLP mapping
- Acquired thrombocytosis [ICD-11 Subcategory]
- Essential (haemorrhagic) thrombocythaemia [ICD-10 Sub-category (who)]
- Essential (hemorrhagic) thrombocythemia [ICD-10 Sub-category]
- Essential thrombocythaemia [MedDRA Preferred Term]
- Essential thrombocythemia [ICD-O code]
- Essential thrombocythemia [PASCAL descriptor]
- Essential thrombocythemia [ICD-11 Extension code]
- Essential thrombocythemia [ICD-9 code]
- Essential thrombocythemia [ORDO Disease]
- Essential thrombocythemia [MedDRA LLT]
- Essential thrombocythemia (morphologic abnormality) [SNOMED CT concept]
- Essential thrombocytosis [ICD-10 Sub-category (who)]
- Essential thrombocytosis [MedDRA LLT]
- Thrombocythemia 1 [OMIM Phenotype]
- essential thrombocythemia [DO Concept]
- essential thrombocytosis [Disease (Nov.)]
- thrombocythemia, essential [MeSH Descriptor]
- thrombocythemia, essential [MeSH concept]
DO Cross reference
- essential thrombocythemia [DO Concept]
Disease excludes abnormal cell
- Neoplastic Erythroblast [NCIt concept]
- Segmented Neutrophil [NCIt concept]
- Tear-Drop Red Blood Cell [NCIt concept]
Disease may have findings
- Hemorrhage [NCIt concept]
- Hepatomegaly [NCIt concept]
- Hypercellular Bone Marrow [NCIt concept]
- Splenomegaly [NCIt concept]
False automatic mappings
- Essential thrombocythemia (disorder) [SNOMED CT concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Acquired thrombocytosis [ICD-11 Subcategory]
- Essential (haemorrhagic) thrombocythaemia [ICD-10 Sub-category (who)]
- Essential (hemorrhagic) thrombocythemia [ICD-10 Sub-category]
- Essential thrombocythaemia [MedDRA Preferred Term]
- Essential thrombocythemia [MedDRA LLT]
- Essential thrombocythemia [ORDO Disease]
- Essential thrombocythemia [ICD-O code]
- Essential thrombocythemia [ICD-9 code]
- Essential thrombocythemia (disorder) [SNOMED CT concept]
- Essential thrombocythemia (morphologic abnormality) [SNOMED CT concept]
- Essential thrombocytosis [MedDRA LLT]
- Essential thrombocytosis [ICD-10 Sub-category (who)]
- Idiopathic thrombocytosis [MedDRA LLT]
- Primary haemorrhagic thrombocythaemia [MedDRA LLT]
- Primary hemorrhagic thrombocythemia [MedDRA LLT]
- essential thrombocythemia [DO Concept]
- essential thrombocytosis [Disease (Nov.)]
- thrombocythemia, essential [MeSH concept]
- thrombocythemia, essential [MeSH Descriptor]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCI CTEP SDC Chronic Myeloproliferative Disease Sub-Category Terminology [NCIt concept]
- NCI CTEP Simplified Disease Classification Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Hematology-Oncology Terminology [NCIt concept]
- mCode Cancer Disorder Value Set [NCIt concept]
- mCode Primary Cancer Disorder Value Set [NCIt concept]
- mCode Primary Malignant Neoplasm Disorder Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_excludes_cytogenetic_abnormality
- Philadelphia Chromosome [NCIt concept]
- t(9;22)(q34.1;q11.2) [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Bone Marrow Dysplasia Present [NCIt concept]
- Bone Marrow Fibrosis [NCIt concept]
- Eosinophilia [NCIt concept]
- Increased Red Cell Mass [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Leukoerythroblastic Reaction [NCIt concept]
- Neutrophilia [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Giant Megakaryocyte [NCIt concept]
- Giant Platelet [NCIt concept]
- Large Atypical Platelet [NCIt concept]
- Large Megakaryocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
disease_has_finding
- Chronic Clinical Course [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Megakaryocytes Increased in Bone Marrow [NCIt concept]
- Thrombocytosis [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Thrombosis [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 8 [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
disease_may_have_molecular_abnormality
- CALR Gene Mutation [NCIt concept]
- JAK2 Gene Mutation [NCIt concept]
- MPL Gene Mutation [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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