DNA-directed RNA Polymerase

Preferred Label : DNA-directed RNA Polymerase;

NCIt synonyms : DNA-Dependent RNA Polymerase; EC 2.7.7.6;

NCIt definition : An enzyme that catalyzes the stepwise addition of ribonucleotides to the 3' end of a growing RNA chain using a single-stranded DNA template. This reaction, transcription, is important in the flow of information from DNA to proteins. Three different polymerase protein complexes have been identified and characterized.;

Details

Origin ID

C17104;

UMLS CUI

C0035681;

Automatic exact mappings (from CISMeF team)
- DRD1 protein, arabidopsis [MeSH Supplementary Concept]
- L polymerase protein, vesicular stomatitis-Indiana virus [MeSH Supplementary Concept]
- MTPAP protein, human [MeSH Supplementary Concept]
- POLR1C protein, human [MeSH Supplementary Concept]
- POLR1D protein, human [MeSH Supplementary Concept]
- POLR2E protein, human [MeSH Supplementary Concept]
- POLR3B protein, human [MeSH Supplementary Concept]
- POLR3E protein, human [MeSH Supplementary Concept]
- POLRMT protein, human [MeSH Supplementary Concept]
- RNA polymerase I [MeSH Descriptor]
- RNA polymerase II [MeSH Descriptor]
- RNA polymerase III [MeSH Descriptor]
- RNA polymerase alpha subunit [MeSH Supplementary Concept]
- RNA polymerase beta subunit [MeSH Supplementary Concept]
- RNA polymerase sigma 54 [MeSH Descriptor]
- RPB5 protein, S cerevisiae [MeSH Supplementary Concept]
- RPC34 protein, S cerevisiae [MeSH Supplementary Concept]
- RPO22 protein, vaccinia virus [MeSH Supplementary Concept]
- RPO41 protein, S cerevisiae [MeSH Supplementary Concept]
- Ribonucleic acid-directed deoxyribonucleic acid polymerase (substance) [SNOMED CT concept]
- Rpb8 protein, S cerevisiae [MeSH Supplementary Concept]
- Rpc19p protein, S cerevisiae [MeSH Supplementary Concept]
- Rpo41 protein, S pombe [MeSH Supplementary Concept]
- RpoTm protein, hordeum vulgare [MeSH Supplementary Concept]
- RpoTmp protein, arabidopsis [MeSH Supplementary Concept]
- RpoTp protein, arabidopsis [MeSH Supplementary Concept]
- RpoTp protein, hordeum vulgare [MeSH Supplementary Concept]
- RpoZ protein, E coli [MeSH Supplementary Concept]
- Trf5 protein, S cerevisiae [MeSH Supplementary Concept]
- taq sigma A [MeSH Supplementary Concept]
Biochemical function of gene products
- DNA-Directed RNA Polymerases I, II, and III Subunit RPABC5 [NCIt concept]
- RNA Polymerase I [NCIt concept]
- RNA Polymerase II [NCIt concept]
Currated CISMeF NLP mapping
- DNA-Directed RNA polymerases [MeSH Descriptor]
- DNA-Directed RNA polymerases [MeSH concept]
- Deoxyribonucleic acid-directed ribonucleic acid polymerase (substance) [SNOMED CT concept]
- dna-directed rna polymerase [SNOMED Notion]
False automatic mappings
- RNA-Directed DNA polymerase [MeSH Descriptor]
- RNA-Directed DNA polymerase [MeSH concept]
- rna-directed dna polymerase [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DNA-Directed RNA polymerases [MeSH concept]
- DNA-Directed RNA polymerases [MeSH Descriptor]
- Deoxyribonucleic acid-directed ribonucleic acid polymerase (substance) [SNOMED CT concept]
- dna-directed rna polymerase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Polymerase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Fidaxomicin [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Phosphorylation Process [NCIt concept]
- Polymerization [NCIt concept]
- RNA Synthesis [NCIt concept]
- Transcription [NCIt concept]
- Transcription Elongation [NCIt concept]
is_target
- Fidaxomicin [NCIt concept]

Keyword's position in hierarchy(ies) :

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