RNA polymerase I

Preferred Label : RNA polymerase I;

MeSH definition : A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin. EC 2.7.7.6.; A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.;

MeSH synonym : dna dependent rna polymerase i; polymerase a, rna; polymerase i, rna; dna-dependent rna polymerase i; rna polymerase a;

CISMeF synonym : i, rna polymerase; a, rna polymerase;

Registry Number MeSH : EC 2.7.7.-; EC 2.7.7.6;

Is substance : O;

UNII : EC 2.7.7.6;

Details

Origin ID

D012318;

UMLS CUI

C0035678;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- DNA-directed RNA Polymerase [NCIt concept]
- Deoxyribonucleic acid-directed ribonucleic acid polymerase (substance) [SNOMED CT concept]
- Nucleotidyltransferase [NCIt concept]
- RNA Polymerase [NCIt concept]
- RNA Polymerase Assembly Pathway [NCIt concept]
Currated CISMeF NLP mapping
- RNA Polymerase I [NCIt concept]
- RNA polymerase I [LOINC component]
- Ribonucleic acid polymerase I (substance) [SNOMED CT concept]
Indexing information
- 9-beta-xylofuranosyladenine 5'-triphosphate [MeSH Supplementary Concept]
- CX 5461 [MeSH Supplementary Concept]
- rpc19 protein, S pombe [MeSH Supplementary Concept]
Record concept(s)
- RNA polymerase I [MeSH concept]
Related MeSH Supplementary Concept(s)
- POLR1G protein, human [MeSH Supplementary Concept]
- RPA12 protein, S cerevisiae [MeSH Supplementary Concept]
- RPA14 protein, S cerevisiae [MeSH Supplementary Concept]
- RPA194 protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RNA Polymerase I [NCIt concept]
- RNA polymerase I [LOINC component]
- Ribonucleic acid polymerase I (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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